2025 Poster Presentations
P144: DEPRESSION AND ANXIETY DO NOT PROLONG LENGTH OF STAY AFTER MENINGIOMA RESECTION
Anne R Lally, BA; Sayak R Ghosh, BS; Isabella L Pecorari, BS; Vijay Agarwal, MD; Albert Einstein College of Medicine
Introduction: Meningiomas are the most common type of primary brain tumor. Their management requires the benefits of definitive resection to be weighed against the potential consequences of surgical complications. To improve outcomes from meningioma resection, modifiable factors that impact prognosis need to be understood. Adverse effects from depression and anxiety have been observed in orthopedic and general surgery procedures. However, the impact of mental illness on recovery from meningioma resection has not yet been studied. The goal of this study is to determine if preoperative depression and anxiety are associated with a greater length of stay after meningioma resection.
Methods: A retrospective review was completed for patients at a single tertiary care center who underwent surgical resection of meningiomas between 2018 and 2023. Demographic information, past medical and psychological history, surgical complications, and length of hospital stay (LOS) after meningioma resection were recorded. Means, standard deviation, and Mann-Whitney U tests were used to evaluate LOS.
Results: A total of 99 patients who underwent surgical resection of a meningioma were included in the analysis, consisting of 31 males (31.3%) and 68 (68.7%) females. Mean patient age at the time of surgery was 62.8 ± 13.6 years. Thirty-seven patients identified as Black (37.4%), 20 as White (20.2%), 3 as Asian (3.0%), and 31 as Other (31.3%). Seven patients did not report their self-identified race (7.1%). Twenty-nine patients (29.3%) were Hispanic. Twenty-three patients were diagnosed with depression (23.2%), and 22 patients had anxiety (22.2%). The mean LOS was 8.26 ± 1.61 days. There is no significant difference in the mean LOS between patients with and those without depression (depression: 7.65 ± 2.87 days; no depression: 8.44 ± 1.94 days; p = 0.481). Moreover, there is no significant difference in the mean LOS between patients with and without anxiety (anxiety: 7.73 ± 2.87 days; no anxiety: 8.40 ± 1.94 days; p = 0.71). Complications after surgery included postoperative DVT (n=4), hemorrhage (n=4), seizure (n=4), PE (n=1), UTI (n=3), myocardial infarction (n=1), and surgical revision (n=1).
Conclusions: Based on the results of this study, anxiety and depression do not have a significant impact on LOS after meningioma resection. This is different from expected based on studies on the effects of psychological disease on length of stay after orthopedic and general surgery procedures. A diagnosis of depression and/or anxiety has no impact on the immediate prognosis of patients after meningioma resection, and thus these psychological conditions should not prevent patients from undergoing surgery. However, more research needs to be conducted on complications beyond the initial postsurgical hospitalization. Another future direction is the ability of patients with mental illness to maintain follow-up visits for monitoring recurrences.