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North American Skull Base Society

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2025 Poster Presentations

2025 Poster Presentations

 

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P176: CRANIAL NODULAR FASCIITIS: CASE REPORT AND SYSTEMATIC REVIEW OF THE LITERATURE
Mariana Agudelo, MD; Sergio Chacón; Wilfran Perez-Mendez; Manuel Vergara; Hospital Universitario San Ignacio

Cranial fasciitis (CF) is a fibroproliferative condition primarily affecting the pediatric population, with origins traced back to post-traumatic events, radiation therapy, hereditary factors, or idiopathic causes. Despite multiple cases reported since its initial classification in 1980, a systematic review encompassing clinical presentation, lesion location, patient history, treatment modalities, follow-up, and recurrence management in both adult and pediatric patients is lacking. CF manifests as a distinctive, indurated, asymptomatic subcutaneous mass, predominantly on the parietotemporal aspect of the calvarium, with potential invasion into the cranial space, necessitating prompt diagnosis and intervention. Diagnostic imaging aids in identification, but histological analysis and complete excision are crucial for definitive diagnosis. The prognosis post-Gross Total Resection (GTR) is favorable, with a low recurrence rate. In this study, we present a case of CF in a 20-month-old girl, providing a comprehensive analysis of significant findings associated with this condition based on a systematic review of existing cases. 

Preoperative imaging. (A-B). CT head. Lytic lesion in the right temporal bone with continuous periosteal reaction. (C-D). MRI showing expansive lesion in the right temporal diploic region, measuring 20x24x27 mm, associated with a discreet increase in the volume of surrounding soft tissues and temporal muscle fibers, with extracranial and intracranial extension.

Histopathology (A-B). Hematoxylin and eosin stain showing spindle-shaped fibroblasts. (C). Immunohistochemically positive for alpha smooth muscle actin?(a-SMA).

Postoperative imaging. CT head. Post-surgical changes from right frontotemporoparietal craniectomy with minimal bleeding in the subgaleal and epidural region; slight compression of the brain parenchyma without herniation.

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