2025 Poster Presentations
P027: FRONTAL SINUS EPIDERMOID TUMOR: CASE REPORT AND LITERATURE REVIEW
Daniel C O'Brien, MD; Doug Hardesty; CHI/Creighton University
Introduction: Epidermoid tumors in the frontal sinus are exceedingly rare, with few cases documented in the literature. These benign but locally aggressive neoplasms can pose significant diagnostic and therapeutic challenges due to their location and potential to cause substantial morbidity. Here we present the case of a 45-year-old woman with a left frontal sinus epidermoid tumor and review of the available English language cases of sinus epidermoid tumors.
Case Presentation: A 45-year-old woman presented with a history of progressive expansion of the left forehead. Clinical evaluation and imaging studies, including CT and MRI, revealed an expansile lesion of the frontal sinus consistent with an epidermoid. Surgical intervention via an open bi-coronal incision and cranialization of the frontal sinus with concurrent cranioplasty was performed. Histopathological examination confirmed the diagnosis of an epidermoid tumor.
.png)
Literature Review: A systematic review of the literature was conducted using PubMed, Scopus, and Web of Science. Key search terms included 'frontal sinus,' 'epidermoid tumor,' 'epidermoid cyst,' and 'sinus cholesteatoma.' Inclusion criteria encompassed all reported cases of sinus epidermoid tumors, with data extracted on patient demographics, clinical presentation, diagnostic methods, treatment modalities, and outcomes. The literature review identified 43 cases of sinus epidermoid tumors. Surgical resection was the primary treatment modality with low rates of recurrence, and favorable long-term prognosis.
Conclusion: Frontal sinus epidermoid tumors, although rare, should be considered in the differential diagnosis of persistent frontal headaches and nasal obstruction. Early diagnosis and surgical intervention are crucial for optimal outcomes. Our case underscores the importance of a multidisciplinary approach, incorporating advanced imaging and surgical techniques